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  • 2023-10-18

    自(zi)(zi)動(dong)取(qu)樣(yang)(yang)(yang)溶出(chu)(chu)儀(yi)是一(yi)種在藥(yao)品(pin)和(he)生(sheng)物樣(yang)(yang)(yang)品(pin)制(zhi)(zhi)備(bei)過(guo)程中(zhong),實現(xian)自(zi)(zi)動(dong)化(hua)取(qu)樣(yang)(yang)(yang)和(he)溶出(chu)(chu)測定的(de)關鍵設備(bei)。它結(jie)合(he)了(le)(le)取(qu)樣(yang)(yang)(yang)、溶出(chu)(chu)、混(hun)(hun)合(he)、分離等多個步(bu)驟,降低了(le)(le)人工操作(zuo)的(de)難度和(he)誤(wu)差,提高了(le)(le)工作(zuo)效率和(he)樣(yang)(yang)(yang)品(pin)制(zhi)(zhi)備(bei)的(de)質量。一(yi)、自(zi)(zi)動(dong)取(qu)樣(yang)(yang)(yang)溶出(chu)(chu)儀(yi)的(de)基本構造和(he)工作(zuo)原理自(zi)(zi)動(dong)取(qu)樣(yang)(yang)(yang)溶出(chu)(chu)儀(yi)通(tong)常由取(qu)樣(yang)(yang)(yang)器(qi)(qi)、溶出(chu)(chu)杯、混(hun)(hun)合(he)器(qi)(qi)、泵、控制(zhi)(zhi)系統等組成。在預(yu)定程序的(de)控制(zhi)(zhi)下,取(qu)樣(yang)(yang)(yang)器(qi)(qi)自(zi)(zi)動(dong)吸取(qu)樣(yang)(yang)(yang)品(pin),并將樣(yang)(yang)(yang)品(pin)輸送至溶出(chu)(chu)杯中(zhong)。在溶出(chu)(chu)杯中(zhong),樣(yang)(yang)(yang)品(pin)與溶劑(ji)混(hun)(hun)合(he),通(tong)過(guo)攪拌(ban)和(he)溫控制(zhi)(zhi)作(zuo)達到(dao)預(yu)設的(de)溶出(chu)(chu)條(tiao)件。最后(hou),溶出(chu)(chu)液通(tong)過(guo)混(hun)(hun)合(he)器(qi)(qi)進行混(hun)(hun)合(he),分離出(chu)(chu)不溶物,并進行后(hou)續的(de)分析...

  • 2023-09-21

    溶(rong)出度測(ce)(ce)定儀(yi)是(shi)(shi)一種用(yong)(yong)(yong)(yong)于(yu)(yu)測(ce)(ce)試藥物溶(rong)出度的(de)儀(yi)器(qi)。溶(rong)出度是(shi)(shi)指藥物從(cong)制劑中(zhong)(zhong)溶(rong)解出來的(de)速度和(he)程(cheng)度,對于(yu)(yu)藥物的(de)有效性(xing)和(he)生物利用(yong)(yong)(yong)(yong)度具(ju)有重要(yao)的(de)影響。因此,溶(rong)出度測(ce)(ce)定儀(yi)在藥品(pin)質(zhi)(zhi)量控(kong)制和(he)研(yan)發中(zhong)(zhong)具(ju)有重要(yao)的(de)作用(yong)(yong)(yong)(yong)。溶(rong)出度測(ce)(ce)定儀(yi)通常由以(yi)下幾(ji)個主要(yao)部分(fen)(fen)組(zu)成(cheng):1.樣(yang)品(pin)容器(qi):通常是(shi)(shi)硬質(zhi)(zhi)或(huo)軟質(zhi)(zhi)的(de)透明容器(qi),用(yong)(yong)(yong)(yong)于(yu)(yu)容納要(yao)測(ce)(ce)試的(de)藥品(pin)。2.攪(jiao)拌裝置:用(yong)(yong)(yong)(yong)于(yu)(yu)混(hun)合樣(yang)品(pin),使(shi)藥物在液體中(zhong)(zhong)充分(fen)(fen)溶(rong)解。3.溫度控(kong)制裝置:用(yong)(yong)(yong)(yong)于(yu)(yu)控(kong)制測(ce)(ce)試過程(cheng)中(zhong)(zhong)的(de)溫度,以(yi)模擬人體內的(de)溫度。4.采樣(yang)裝置:用(yong)(yong)(yong)(yong)于(yu)(yu)定時從(cong)樣(yang)品(pin)容器(qi)中(zhong)(zhong)取(qu)樣(yang),以(yi)測(ce)(ce)量藥物的(de)溶(rong)解程(cheng)度。5.數(shu)據記(ji)...

  • 2023-09-18

  • 2023-09-15

    自(zi)(zi)動(dong)(dong)取(qu)(qu)樣(yang)溶(rong)出(chu)儀(yi)是(shi)一(yi)種用(yong)于(yu)自(zi)(zi)動(dong)(dong)取(qu)(qu)樣(yang)并測定(ding)固體(ti)或液體(ti)樣(yang)品(pin)(pin)溶(rong)解(jie)(jie)性(xing)的儀(yi)器(qi)(qi)(qi)(qi)。它廣泛(fan)應用(yong)于(yu)化(hua)學、生物、制藥(yao)、環(huan)保等領域,對于(yu)研究(jiu)物質的溶(rong)解(jie)(jie)性(xing)質、藥(yao)物釋放(fang)行為以(yi)及固體(ti)廢(fei)物處(chu)理(li)等方(fang)面具(ju)有重要(yao)意義。自(zi)(zi)動(dong)(dong)取(qu)(qu)樣(yang)溶(rong)出(chu)儀(yi)的主要(yao)結構包括取(qu)(qu)樣(yang)器(qi)(qi)(qi)(qi)、樣(yang)品(pin)(pin)容器(qi)(qi)(qi)(qi)、泵(beng)、控制系(xi)統和數(shu)據(ju)處(chu)理(li)系(xi)統等部(bu)分(fen)。它的工作原理(li)是(shi):通(tong)過泵(beng)將(jiang)溶(rong)劑從溶(rong)劑容器(qi)(qi)(qi)(qi)中抽出(chu),然后通(tong)過管(guan)道輸送到樣(yang)品(pin)(pin)容器(qi)(qi)(qi)(qi)中,將(jiang)樣(yang)品(pin)(pin)溶(rong)解(jie)(jie)在溶(rong)劑中。在設定(ding)的時間(jian)間(jian)隔(ge)內,通(tong)過取(qu)(qu)樣(yang)器(qi)(qi)(qi)(qi)自(zi)(zi)動(dong)(dong)取(qu)(qu)樣(yang),并由數(shu)據(ju)處(chu)理(li)系(xi)統進(jin)行數(shu)據(ju)處(chu)理(li)和分(fen)析。自(zi)(zi)動(dong)(dong)取(qu)(qu)樣(yang)溶(rong)出(chu)儀(yi)具(ju)有以(yi)下優(you)點(dian):1.自(zi)(zi)動(dong)(dong)化(hua)程(cheng)度高(gao):自(zi)(zi)...

  • 2023-08-28

    附件參考(kao):huaxuefangzhiyaocanbizhijimuludiqishiyipi.docx

  • 2023-08-24

    溶(rong)(rong)媒(mei)(mei)制(zhi)(zhi)備儀是(shi)一種用(yong)于(yu)制(zhi)(zhi)備溶(rong)(rong)媒(mei)(mei)的實驗(yan)室設備。它(ta)可以幫助科(ke)學家們在研究和(he)(he)實驗(yan)中(zhong)(zhong)(zhong),快速、準確(que)地生成溶(rong)(rong)媒(mei)(mei),從而進行各種化學反應和(he)(he)實驗(yan)。溶(rong)(rong)媒(mei)(mei)制(zhi)(zhi)備儀通(tong)常由一個(ge)(ge)容(rong)器(qi)(qi)、一個(ge)(ge)攪拌器(qi)(qi)、一個(ge)(ge)溫(wen)度控(kong)(kong)制(zhi)(zhi)器(qi)(qi)和(he)(he)一個(ge)(ge)泵(beng)組成。容(rong)器(qi)(qi)用(yong)于(yu)容(rong)納溶(rong)(rong)劑(ji)和(he)(he)溶(rong)(rong)質,攪拌器(qi)(qi)用(yong)于(yu)將溶(rong)(rong)質溶(rong)(rong)解(jie)在溶(rong)(rong)劑(ji)中(zhong)(zhong)(zhong),溫(wen)度控(kong)(kong)制(zhi)(zhi)器(qi)(qi)用(yong)于(yu)控(kong)(kong)制(zhi)(zhi)溶(rong)(rong)液的溫(wen)度,而泵(beng)則用(yong)于(yu)將溶(rong)(rong)液轉移至其他(ta)設備或實驗(yan)室中(zhong)(zhong)(zhong)。溶(rong)(rong)媒(mei)(mei)制(zhi)(zhi)備儀的使(shi)用(yong)過(guo)程相對簡單。首先,用(yong)戶需(xu)要選(xuan)擇適(shi)合的溶(rong)(rong)劑(ji)和(he)(he)溶(rong)(rong)質,并將它(ta)們放入容(rong)器(qi)(qi)中(zhong)(zhong)(zhong)。然后,啟動攪拌器(qi)(qi),使(shi)溶(rong)(rong)質充(chong)分溶(rong)(rong)解(jie)在溶(rong)(rong)劑(ji)中(zhong)(zhong)(zhong)。接下來,溫(wen)度控(kong)(kong)制(zhi)(zhi)器(qi)(qi)可以用(yong)來升高或降...

  • 2023-08-21

  • 2023-08-16

    自動溶出(chu)儀是一種用(yong)于(yu)測(ce)量(liang)(liang)(liang)藥物(wu)(wu)或保(bao)健(jian)品(pin)等在(zai)模擬人(ren)(ren)體(ti)(ti)消化系(xi)統中溶解(jie)速(su)(su)度(du)的(de)(de)設(she)備(bei)。它對于(yu)研究藥物(wu)(wu)動力學、評(ping)估(gu)藥物(wu)(wu)療效、檢測(ce)藥品(pin)質(zhi)量(liang)(liang)(liang)以(yi)及(ji)評(ping)估(gu)保(bao)健(jian)品(pin)的(de)(de)生物(wu)(wu)利用(yong)度(du)等方面具有(you)重要作用(yong)。自動溶出(chu)儀的(de)(de)主要組成部(bu)分包括一個溶出(chu)杯,用(yong)于(yu)容(rong)納待測(ce)樣品(pin);一個恒(heng)溫水(shui)槽,模擬人(ren)(ren)體(ti)(ti)體(ti)(ti)溫;一個旋轉裝置(zhi),使(shi)樣品(pin)在(zai)溶出(chu)杯中均勻溶解(jie);以(yi)及(ji)一個檢測(ce)系(xi)統,用(yong)于(yu)測(ce)量(liang)(liang)(liang)樣品(pin)的(de)(de)溶解(jie)速(su)(su)度(du)。使(shi)用(yong)自動溶出(chu)儀時,需要先將(jiang)待測(ce)樣品(pin)放(fang)入溶出(chu)杯中,然后加入模擬人(ren)(ren)體(ti)(ti)消化系(xi)統的(de)(de)溶液。接著,將(jiang)溶出(chu)杯放(fang)置(zhi)在(zai)恒(heng)溫水(shui)槽中,并設(she)定旋轉速(su)(su)度(du)。在(zai)樣品(pin)溶解(jie)的(de)(de)過(guo)程...

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